Clinical Chemistry

Clinical chemistry (also known as chemical pathology) extends across most medical specialities and involves the biochemical investigation of bodily fluids (blood – whole blood, serum or plasma; urine; cerebrospinal fluid; and other fluids such as effusions, seminal fluid, sweat and amniotic fluid). Clinicians rely on this essential information to aid diagnosis as well as management and follow-up of patients.

The Clinical Chemistry laboratory provides routine and state of the art specialized assays for patient care. These include but are not limited to:

Routines tests: urea and electrolytes (kidney function), liver function, glucose, calcium, magnesium, lipids, protein electrophoresis (paraprotein)

Diabetes diagnostic tests: glucose, glucose tolerance test, glucose challenge test in pregnancy, HbA1C, C-peptide, quick index

Cardiac markers: Troponin, pro-BNP

Mineral and vitamins: iron studies, vitamin B12, folate, vitamin D

Endocrinology: thyroid function, cortisol, testosterone, oestrogen, anti-mullerian hormone, infertility screen prolactin, pituitary hormones

Tumour markers: PSA (prostate specific antigen), CEA, Ca 125, Ca 19-9, AFP

Therapeutic Drug Monitoring: carbamazepine, sodium valproate, ciclosporin, tacrolimus, gentamicin, vancomycin

Toxicology: screening for drugs of abuse

Occupational testing: heavy metal studies, industrial screening

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